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Types of Medication for Cystitis: Characteristics and Contraindications

Antibiotics are probably the most commonly used medications for cystitis. However, there are other useful options for relieving the symptoms of the disease.

Types of drugs for cystitis: characteristics and contraindications

Last actualisation: March 29, 2023

Cystitis is an infection of the lower urinary tract that happens when certain bacteria reach the bladder. This pathology may be very irritating and must be treated as soon as possible. Do you wish to learn about the differing types of cystitis medications? Here we’ll let you know about the several options.

Studies they showed it Urinary tract infections are amongst probably the most common reasons for visits to the doctor. Symptoms range from pain and difficulty urinating to cloudy urine with a robust or unpleasant odor.

Early diagnosis and prompt treatment of this condition is crucial to improving the health prognosis. Therapeutic failure or delay in skilled approach favors the emergence of complications within the medium and long run.

5 forms of drugs for cystitis

The treatment of cystitis goals to eliminate the bacteria responsible and thus relieve the discomfort. The medications you select for cystitis will rely on whether the infection is acute or chronic. Treatment options include:

1. Antibiotics

It is the drug of first selection for cystitisbecause they’re liable for eliminating the causative agent. According to research, the microorganisms that almost all often cause urinary tract infections are people who inhabit the digestive tract, resembling Escherichia coli. Here are some antibiotics which are effective against these bacteria:

  • Fosfomycin: It is one in every of the drugs used to treat urinary tract infections. The really useful dose is 1 sachet of 8 grams at a time or every 24 hours for two days.
  • Nitrofurantoin: Nitrofurantoin is one other effective treatment for cystitis. The dosage is frequently 1 capsule of 100 milligrams every 6 hours for 7 to 10 days. Like fosfomycin, nitrofurantoin has minimal effect on normal intestinal flora tests.
  • Trimethoprim-sulfamethoxazole: It is a mix of two pharmacological compounds which are particularly effective against Escherichia coli and other enterobacteria. Its dosage is frequently 1 or 2 tablets every 12 hours for a minimum of 5 days.
  • Penicillins and cephalosporins: These are compounds that work by inhibiting the formation of a wall covering the bacteria. Their dosage is different for every group of medicine. Some of the penicillins used are ampicillin and amoxicillin with clavulanic acid.
  • Fluoroquinolones: They aren’t often used for uncomplicated urinary tract infections because the risks outweigh the advantages most often. Ofloxacin, ciprofloxacin, and levofloxacin are among the most useful.


The major contraindication to taking antibiotics for cystitis is an allergy to the lively substanceespecially with penicillin. Ingestion of those drugs by allergy victims may cause a life-threatening generalized inflammatory response.

In addition, pregnant or lactating women should seek the advice of a specialist beforehand, as it could affect the infant. Children under 3 months of age and folks with kidney disease need special doses.

Antibiotics are the primary selection against cystitis because they attack the causative agent.

2. Antispasmodics and painkillers

Pain and burning when urinating are frequently probably the most irritating symptoms of cystitis. Other symptoms that cause discomfort include urinary urgency, abdominal pain, and increased frequency of urination. Fortunately, medications for cystitis include antispasmodics and painkillers.

Antispasmodics resembling scopolamine and flavoxate help relieve symptoms. Both they prevent bladder spasms, which reduces pain and frequency of urination.

Phenazopyridine is an analgesic that acts on the urinary tract, so it’s capable of relieve the pain related to cystitis. In fact, a study in a journal Urology showed that it’s a useful drug and well tolerated by individuals with uncomplicated cystitis.


Both scopolamine and flavoxate are contraindicated in pathologies of urinary tract obstructionin addition to pyloric and paralytic ileus. This is because they reduce the natural peristalsis of the intestines and deepen these pathologies. Scopolamine can be contraindicated myasthenia gravis hard and narrow-angle glaucoma.

Phenazopyridine is contraindicated in children under 12 years of age. In addition, it must be used with extreme caution in individuals with liver or kidney disease.

3. Antiseptics

Other medications which are useful in treating cystitis are antiseptics. Research describes them as chemical compounds applied to the skin or mucous membranes to inhibit the expansion of bacteria. In this case, methenamine and methylthioninium chloride are mostly used.

Both compounds are capable of eliminate germs from the urinary tract, thus relieving symptoms inside a couple of days. In addition, studies assume that methenamine is usually prescribed to forestall relapses of cystitis within the short term.


Under no circumstances should methenamine be utilized in individuals with severe liver or kidney failure or in individuals with metabolic acidosis. This is because these clinical pictures can worsen and put the patient’s life in danger.

4. Anti-inflammatory drugs

According to research, non-steroidal anti-inflammatory drugs (NSAIDs) resembling ibuprofen are used to treat the discomfort of cystitis in the primary place. Thanks to their mechanism of motion, they reduce inflammation within the bladderwhich relieves pain and burning during urination.

The effectiveness of those compounds may be enhanced when taken along with spasmolytic agents resembling scopolamine. As mentioned above, the latter will reduce bladder and urethral spasms, providing further relief.


Anti-inflammatory drugs are secure for most individuals. Their use is contraindicated only in patients with a history of conditions related to their intake, resembling bronchospasm, urticaria or bleeding from the gastrointestinal tract.

5. Vaccines for urinary tract infections

There are useful methods of immunization to treat and forestall cystitis, resembling by probability Uro-vaxom ®. It is a tablet containing greater than 10 strains of Escherichia coliwhich, as already mentioned, is the leading reason for urinary tract infections worldwide.

The drug has the power to activate the immune system to fight the colonization and invasion of those bacteria. Study published within the journal Current urology states that it’s an efficient therapy to forestall recurrent urinary tract infections.


The vaccine in tablets is one in every of the safest drugs on all the list and the one contraindication is an allergy to any of the ingredients of the drug. Treatment must be stopped if any skin response is observed, resembling hives, swelling or fever.

Its effectiveness in children under 4 years of age has not yet been demonstrated.

Other medications for cystitis

All of the medications listed above are useful in acute cystitis, but treatment options for chronic or recurrent cases may vary. Interstitial cystitis is some of the severe variants, so its approach must be more aggressive by combining the next options:

  • Antihistamines: They reduce the frequency of urination. One of the drugs on this group is loratadine.
  • Pentosan Sodium Polysulfate: It is believed to guard the inner partitions of the bladder against irritants, although its mechanism of motion just isn’t fully understood. It reduces organ damage and relieves pain during urination.
  • Tricyclic antidepressants: Thanks to their affinity for a lot of receptors, they calm down the bladder and block pain, bringing relief. The drugs utilized in this case are amitriptyline and imipramine.
Once the responsible bacteria are identified, a precise antibiotic may be prescribed to the patient. Other medications help ease the discomfort.

Some recommendations and residential remedies

It is feasible to make some lifestyle changes to cut back the discomfort of cystitis. Some recommendations are as follows:

  • Drinking loads of water
  • Limiting the consumption of irritating drinks, sodas and lemon juices.
  • Avoiding coffee and alcohol.
  • Applying warm compresses to the lower abdomen to cut back pressure at this level.

In addition, there are some home remedies that may be useful in stopping and controlling this condition. It is price emphasizing, nonetheless they aren’t an alternative to prescribed medications for cystitis.

A study published in Nutrition Diary showed that eating cranberries reduces the likelihood of urinary tract infections by as much as 26%.

Herbal teas resembling dandelion and parsley have been shown to be effective. They have diuretic propertiesthus stopping the colonization of bacteria within the urinary tract.

Multiple options for a similar condition

As you possibly can see, there are various forms of medications for cystitis. Most of them are aimed toward eliminating the causative agent. However, there are also compounds used to cut back and relieve symptoms.

Before using any of the choices we’re talking about, it’s at all times price consulting a specialist. Medical staff will give you the option to discover the causative agent and prescribe appropriate treatment.

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